Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26546933 | 0.88 | HTR6 (0.33) | — | |
| SCHEMBL9044557 | 0.78 | — | — | |
| SCHEMBL5376368 | 0.78 | — | — | |
| SCHEMBL14862826 | 0.72 | HTR6 (0.37) | HTR2AHTR2C | |
| SCHEMBL2670282 | 0.70 | — | — | |
| SCHEMBL7490307 | 0.70 | CTDSP1 (0.32) | — | |
| SCHEMBL13813915 | 0.67 | L3MBTL3 (0.35) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL18518972 | 0.66 | SMN1; SMN2 (0.43) | ALDH1A1MAPT | |
| SCHEMBL27729342 | 0.65 | HTR2C (0.33) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL2265420 | 0.64 | HTR2C (0.33) | MEN1ALDH1A1MAPTPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142528-B1 | 1-(1-BENZYLPIPERIDIN-4-YL)BENZIMIDAZ0LE -5-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES MELLITUS | HOFFMANN LA ROCHE (CH) | 2010-07-07 | — | — | EP | disclosed |