Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818119 | 0.76 | KDM4E (0.34) | MEN1KMT2ALMNAMAPTCNR1 | |
| SCHEMBL27770330 | 0.75 | CHRM1 (0.43) | LMNATSHRCNR2 | |
| SCHEMBL27926249 | 0.74 | PTPN1 (0.34) | CNR2ALDH1A1 | |
| SCHEMBL27952647 | 0.73 | P2RX3 (0.34) | MAPTALOX15SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28035914 | 0.73 | KMT2A (0.33) | MEN1KMT2ALMNAHSD17B10USP2 | |
| SCHEMBL27997552 | 0.72 | CREBBP (0.38) | LMNATSHRCNR1CNR2HPGD | |
| SCHEMBL27951823 | 0.72 | CNR2 (0.41) | CNR1CNR2 | |
| SCHEMBL28341398 | 0.72 | CCNE2 (0.38) | MEN1KMT2ALMNATSHRMAPT | |
| SCHEMBL27670405 | 0.72 | CNR2 (0.34) | CNR1CNR2 | |
| SCHEMBL28760252 | 0.72 | LMNA (0.31) | MEN1KMT2ALMNAUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326177-A | Dihydroisoindolones as allosteric modulators of glucokinase | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-17 | — | — | CN | disclosed |