Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP10 | P09238 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552135 | 0.74 | FKBP1A (0.47) | ALDH1A1HTTMMP8MMP12MMP13 | |
| SCHEMBL6831374 | 0.70 | FKBP1A (0.54) | ALDH1A1HTTMMP8MMP12MMP13 | |
| SCHEMBL6831371 | 0.70 | FKBP1A (0.54) | ALDH1A1HTTMMP8MMP12MMP13 | |
| SCHEMBL27729685 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HTTMMP8MMP12MMP13 | |
| Hydroxyamine SCHEMBL5894442 | 0.69 | FKBP1A (0.50) | ALDH1A1HTTMMP8MMP12MMP13 | |
| SCHEMBL27733114 | 0.68 | MMP8 (0.48) | ALDH1A1MMP8MMP12MMP13FKBP1A | |
| SCHEMBL27732965 | 0.68 | MMP8 (0.43) | ALDH1A1MMP8MMP12MMP13PLAU | |
| SCHEMBL6963805 | 0.68 | ALDH1A1 (0.46) | ALDH1A1HTTMMP8MMP12MMP13 | |
| SCHEMBL11602971 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HTTMMP8MMP12MMP13 | |
| SCHEMBL27732967 | 0.68 | MMP8 (0.42) | ALDH1A1MMP8MMP12MMP13PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351453-A | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-21 | — | — | CN | disclosed |