Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581905 | 0.96 | NLRP3 (0.40) | LPAR1LPAR5LPAR2C5AR1GCGR | |
| SCHEMBL3577892 | 0.90 | SLC2A1 (0.40) | LPAR1LPAR5LPAR2C5AR1ATM | |
| SCHEMBL27750937 | 0.86 | C5AR1 (0.40) | LPAR1LPAR5LPAR2C5AR1NLRP3 | |
| SCHEMBL27750952 | 0.85 | NLRP3 (0.40) | LPAR1LPAR2NLRP3 | |
| SCHEMBL3576630 | 0.84 | LPAR1 (0.37) | LPAR1LPAR5LPAR2C5AR1ATM | |
| SCHEMBL3576449 | 0.83 | LPAR1 (0.39) | LPAR1LPAR5LPAR2C5AR1ATM | |
| SCHEMBL3576381 | 0.83 | STAT3 (0.38) | LPAR1LPAR5LPAR2ATM | |
| SCHEMBL3581285 | 0.82 | LPAR1 (0.36) | LPAR1LPAR5LPAR2C5AR1ATM | |
| SCHEMBL3572707 | 0.81 | CCR9 (0.42) | LPAR1LPAR5LPAR2C5AR1ATM | |
| SCHEMBL3579102 | 0.80 | LPAR1 (0.41) | LPAR1LPAR5LPAR2C5AR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379036-B | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| CN-101379036-A | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | disclosed |