SCHEMBL27730652

SCHEMBL27730652

CC[Si](Cc1ccccc1)(OC(C)=O)OC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
LMNA P02545 2/20 0.39
MAOB P27338 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
AKR1B1 P15121 1/20 0.38
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
PTGS2 P35354 1/20 0.37
TSHR P16473 1/20 0.37
TP53 P04637 1/20 0.37
RECQL P46063 1/20 0.36
GAA P10253 1/20 0.36
ALPI P09923 1/20 0.36
PKM P14618 1/20 0.36
PTGS1 P23219 1/20 0.36
XIAP P98170 1/20 0.36
SLC7A5 Q01650 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10797892 0.92 ALDH1A1 (0.52) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL1087067 0.82 ALDH1A1 (0.42) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL1087314 0.82 ALDH1A1 (0.42) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL1087867 0.82 ALDH1A1 (0.42) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL476083 0.81 ALDH1A1 (0.52) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL3887279 0.81 ALDH1A1 (0.52) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL476074 0.79 ALDH1A1 (0.50) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL27730660 0.79 ALDH1A1 (0.50) ALDH1A1LMNAMAOBCES2CES1
SCHEMBL3973273 0.79 LMNA (0.47) ALDH1A1LMNACES2CES1TSHR
SCHEMBL27710216 0.76 ALDH1A1 (0.47) ALDH1A1LMNAMAOBCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101646718-B Curable resin composition, protective film, and method for forming protective film JSR CORP JP 2013-04-03 CN disclosed
CN-101226329-B Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP 2012-09-05 CN disclosed
CN-101646718-A The formation method of curable resin composition, protective membrane and protective membrane JSR CORP JP 2010-02-10 CN disclosed
CN-101226329-A Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP (JP) 2008-07-23 CN disclosed