Sugi Predict

Sugi Predict / Compounds / SCHEMBL476083

SCHEMBL476083

SCHEMBL476083

CC(=O)O[Si](Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.52
▸ LMNA P02545 2/20 0.41
▸ CES2 O00748 1/20 0.40
▸ CES1 P23141 1/20 0.40
▸ AKR1B1 P15121 1/20 0.40
▸ MAOB P27338 1/20 0.40
▸ PTGS2 P35354 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NOS2 P35228 1/20 0.38
▸ ALPI P09923 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ PTGS1 P23219 1/20 0.38
▸ XIAP P98170 1/20 0.38
▸ SLC7A5 Q01650 1/20 0.38
▸ PPARG P37231 1/20 0.38
▸ PPARA Q07869 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ MTNR1A P48039 1/20 0.38
▸ MTNR1B P49286 1/20 0.38
▸ KEAP1 Q14145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887279 0.84 ALDH1A1 (0.52) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL10797892 0.84 ALDH1A1 (0.52) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL5839431 0.83 ALDH1A1 (0.43) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL476074 0.82 ALDH1A1 (0.50) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL27730660 0.82 ALDH1A1 (0.50) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL1087867 0.81 ALDH1A1 (0.42) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL1087314 0.81 ALDH1A1 (0.42) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL1087067 0.81 ALDH1A1 (0.42) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL27730652 0.81 ALDH1A1 (0.48) ALDH1A1LMNACES2CES1AKR1B1
SCHEMBL476081 0.80 PLA2G10 (0.41) ALDH1A1LMNACES2CES1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 — — US claimed
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof GILLARD MICHEL 2010-09-30 — — US claimed
US-20070161722-A1 Silyl Esters, Their Use in Binder Systems and Paint Compositions and a Process for Production Thereof SIGMA COATINGS B.V. (NL) 2007-07-12 — — US claimed
EP-1606329-A1 A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN SigmaKalon B.V. (NL) 2005-12-21 — — EP claimed
EP-1606338-A1 A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS SigmaKalon B.V. (NL) 2005-12-21 — — EP claimed
US-20050222446-A1 Process for the production of hydrocarbyl silyl carboxylate compounds SIGMA COATINGS B.V. (NL) 2005-10-06 — — US claimed
EP-1572701-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2005-09-14 — — EP claimed
WO-2004085518-A1 A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS SIGMAKALON B.V. (NL) 2004-10-07 — — WO claimed
WO-2004085502-A1 A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN SIGMAKALON B.V. (NL) 2004-10-07 — — WO claimed
EP-1462472-A1 A process for the protection of acid groups in polymers Sigma Kalon Services B.V. (NL) 2004-09-29 — — EP claimed
EP-1462467-A1 A process for the production of silyl group containing polymer resin Sigma Kalon Services B.V. (NL) 2004-09-29 — — EP claimed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 — — WO claimed
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 — — EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 — — EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 — — EP disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 — — WO disclosed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 — — WO disclosed
WO-2004005302-A1 PROCESS FOR THE PREPARATION OF ACYLOXYSILANES SIGMA COATINGS B.V. (NL) 2004-01-15 — — WO disclosed
EP-1378514-A1 Process for the preparation of acyloxysilanes SigmaKalon Group B.V. (NL) 2004-01-07 — — EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof LCT, PCMT1, TST ALDH1A1 2426/4885LMNA 3691/4885CES2 461/4885
US-20050222446-A1 Process for the production of hydrocarbyl silyl carboxylate compounds FTO, SUCLG2, ALKBH3 ALDH1A1 212/4885LMNA 3152/4885CES2 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.