Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730967 | 0.84 | MEN1 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27731011 | 0.82 | HTT (0.47) | RARBCHEK1MAP4K4LCKCSF1R | |
| SCHEMBL9453349 | 0.80 | MEN1 (0.62) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28025514 | 0.80 | RARB (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27731010 | 0.80 | LMNA (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27731003 | 0.80 | LMNA (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28774632 | 0.79 | PARP1 (0.39) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL15412857 | 0.79 | PARP1 (0.58) | MEN1KMT2ACHEK1MAP4K4PARP1 | |
| SCHEMBL28770640 | 0.78 | MCL1 (0.54) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28774631 | 0.78 | PTPN11 (0.49) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373939-A | 4-methoxy-N, N'-bisubstituted phenyl-1, 3-benzene diamide compounds as well as preparation method and application thereof | UNIV TIANJIN TECHNOLOGY | 2013-10-30 | — | — | CN | claimed |
| CN-103373939-A | 4-methoxy-N, N'-bisubstituted phenyl-1, 3-benzene diamide compounds as well as preparation method and application thereof | UNIV TIANJIN TECHNOLOGY | 2013-10-30 | — | — | CN | disclosed |