Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731888 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27711184 | 0.81 | MEN1 (0.49) | ALDH1A1CA2PPARGCHRNA7HPGD | |
| SCHEMBL1633279 | 0.81 | MEN1 (0.49) | ALDH1A1HSP90AB1HMGCRKDM4EHPGD | |
| SCHEMBL27711215 | 0.79 | ELANE (0.39) | ALDH1A1HSP90AB1HMGCRKDM4ECA2 | |
| SCHEMBL27731867 | 0.78 | ELANE (0.39) | ALDH1A1HSP90AB1HMGCRKDM4EPPARG | |
| SCHEMBL28138982 | 0.76 | MTNR1A (0.45) | ALDH1A1KDM4EHPGDGAA | |
| Hydrochloric Acid SCHEMBL10430283 | 0.75 | MTNR1A (0.44) | ALDH1A1KDM4EHPGD | |
| SCHEMBL2587493 | 0.74 | STS (0.54) | ALDH1A1STSPPARGGAASMN1; SMN2 | |
| SCHEMBL6260242 | 0.74 | CYP2C19 (0.44) | ALDH1A1HSP90AB1KDM4E | |
| SCHEMBL27711220 | 0.73 | GAA (0.42) | ALDH1A1HSP90AB1KDM4ECA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |