Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732009 | 0.92 | HTT (0.58) | MAPTALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL27711760 | 0.91 | MAPT (0.52) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL27711764 | 0.88 | MAPT (0.58) | MAPTALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL27731981 | 0.83 | MAPT (0.59) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL4501702 | 0.82 | DGAT1 (0.59) | MAPTALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL27732011 | 0.79 | MAPT (0.72) | MAPTALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL18737412 | 0.76 | MAPT (0.79) | MAPTALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL4506516 | 0.75 | HTT (0.59) | MAPTALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL27732014 | 0.74 | MAPT (0.51) | MAPTALDH1A1KDM4ENPC1PKM | |
| SCHEMBL27732017 | 0.72 | NAMPT (0.45) | MAPTALDH1A1KDM4ENPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | claimed |
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |