Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711760 | 0.92 | MAPT (0.52) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL27732009 | 0.91 | HTT (0.58) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27732011 | 0.85 | MAPT (0.72) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL27731978 | 0.83 | MAPT (0.54) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4517518 | 0.81 | MAPT (0.60) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL27711764 | 0.81 | MAPT (0.58) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL27732014 | 0.77 | MAPT (0.51) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL15979566 | 0.76 | GFER (0.59) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL4506770 | 0.74 | DGAT1 (0.59) | MAPTALDH1A1USP2HSD17B10KMT2A | |
| SCHEMBL27731980 | 0.74 | DGAT1 (0.51) | MAPTALDH1A1USP2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | claimed |
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |