Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498080 | 0.79 | DGAT1 (0.79) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL27731980 | 0.79 | DGAT1 (0.51) | MAPTSMN1; SMN2LMNADGAT1CYP2C19 | |
| SCHEMBL27711767 | 0.75 | WNT3A (0.56) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL1399272 | 0.73 | MAPT (0.68) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL27711811 | 0.70 | RAB9A (0.52) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL4497793 | 0.70 | DGAT1 (0.82) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL50482 | 0.69 | MAPT (0.69) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL27711777 | 0.68 | RAB9A (0.48) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL29301634 | 0.68 | MAPT (0.61) | MAPTSMN1; SMN2LMNAHTTDGAT1 | |
| SCHEMBL4247738 | 0.68 | MAPT (0.86) | MAPTSMN1; SMN2LMNAHTTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | claimed |
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |