Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732656 | 0.81 | KDM4E (0.34) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL1877071 | 0.75 | NOTUM (0.55) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL29599871 | 0.75 | NOTUM (0.55) | MEN1KMT2AKDM4EMAPTGAA | |
| Indoline SCHEMBL22344733 | 0.73 | NOTUM (0.46) | MEN1KMT2AMAPTGAANOTUM | |
| SCHEMBL18554680 | 0.73 | ASIC3 (0.46) | MAPTPNMT | |
| SCHEMBL17785849 | 0.72 | AXL (0.41) | NOTUM | |
| SCHEMBL158725 | 0.70 | NOTUM (0.59) | MEN1KMT2AMAPTNOTUMBCHE | |
| SCHEMBL29807547 | 0.70 | NOTUM (0.59) | MEN1KMT2AMAPTNOTUMBCHE | |
| SCHEMBL4718616 | 0.69 | KDM4E (0.63) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL28212105 | 0.68 | PARP10 (0.45) | MEN1KMT2AKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101257948-A | Pyrimidine-fused diazepine derivatives and indole-fused pteridines | ATTENUON LLC (US) | 2008-09-03 | — | — | CN | disclosed |