Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718535 | 0.75 | PARP10 (0.64) | PARP10PARP11MEN1KMT2AKDM4E | |
| SCHEMBL29648250 | 0.75 | PARP10 (0.64) | PARP10PARP11MEN1KMT2AKDM4E | |
| SCHEMBL28212644 | 0.69 | ALDH1A1 (0.34) | PARP10PARP11MAPTALDH1A1CDK2 | |
| SCHEMBL27593794 | 0.68 | PARP11 (0.47) | PARP10PARP11MEN1KMT2AKDM4E | |
| SCHEMBL9642594 | 0.68 | PARP10 (0.50) | PARP10PARP11MEN1KMT2AKDM4E | |
| SCHEMBL27732858 | 0.68 | MEN1 (0.49) | PARP10PARP11MEN1KMT2AKDM4E | |
| SCHEMBL14785203 | 0.66 | PARP10 (0.51) | PARP10PARP11MEN1KMT2AKDM4E | |
| SCHEMBL2099508 | 0.65 | BACE1 (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL5544098 | 0.65 | NOTUM (0.44) | PARP10PARP11MEN1KMT2AALDH1A1 | |
| SCHEMBL20539302 | 0.64 | NOTUM (0.47) | PARP10PARP11MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849013-A | It is used for the cyanopyrrole alkanes for the treatment of cancer as DUB inhibitor | 特殊治疗有限公司 | 2018-03-27 | — | — | CN | disclosed |