Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555140 | 0.88 | CA1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14341400 | 0.83 | ABL1 (0.47) | GAALMNANFKB1NFKB2RELA | |
| SCHEMBL23118250 | 0.83 | GAA (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9944141 | 0.81 | LMNA (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31160526 | 0.81 | GAA (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23089980 | 0.81 | GAA (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15958202 | 0.81 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8335189 | 0.80 | NOTUM (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23089981 | 0.80 | GAA (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22400342 | 0.80 | CA12 (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103641795-A | Acetophenone derivatives containing 1,2,3-thiadiazole and preparation method and use thereof | UNIV NANKAI | 2014-03-19 | — | — | CN | claimed |
| CN-102382108-A | Tetrazole compounds containing 1,2,3-bismuththiol methylene, preparation methods for same and application thereof | UNIV NANKAI | 2012-03-21 | — | — | CN | claimed |
| CN-101891709-A | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | claimed |
| CN-103641795-B | One class contains acetophenone derivs of 1,2,3-thiadiazoles and its production and use | NANKAI UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-102382108-B | Tetrazole compounds containing 1,2,3-bismuththiol methylene, preparation methods for same and application thereof | UNIV NANKAI | 2014-11-19 | — | — | CN | disclosed |
| CN-103641795-A | Acetophenone derivatives containing 1,2,3-thiadiazole and preparation method and use thereof | UNIV NANKAI | 2014-03-19 | — | — | CN | disclosed |
| CN-101891709-B | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2012-11-21 | — | — | CN | disclosed |
| CN-102382108-A | Tetrazole compounds containing 1,2,3-bismuththiol methylene, preparation methods for same and application thereof | UNIV NANKAI | 2012-03-21 | — | — | CN | disclosed |
| CN-101891709-A | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | disclosed |
| CN-101235044-B | Method for preparing faropenem daloxate | NANJING HUAWEI MEDICAL SCIENCE & TECHNOLOGY CO LTD | 2010-11-03 | — | — | CN | disclosed |
| CN-101235044-A | Method for preparing faropenem daloxate | NANJING HUAWEI MEDICAL SCIENCE (CN) | 2008-08-06 | — | — | CN | disclosed |