Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733247 | 0.88 | CA12 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9944141 | 0.88 | LMNA (0.60) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29947637 | 0.87 | ALDH1A1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL22400342 | 0.87 | CA12 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2811746 | 0.87 | ALDH1A1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13696427 | 0.87 | CNR2 (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8335189 | 0.87 | NOTUM (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29796046 | 0.87 | CA12 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8336066 | 0.84 | CA1 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL23213813 | 0.84 | CA12 (0.43) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201152-B1 | HEATING MIXTURE OF METHYL-3,5-DICHLORO-4-METHYLBENZOATE AND ALPHA,ALPHA,ALPHA-TRICHLOROMETHYLBENZENE IN PRESENCE OF AMMONIUM MOLYBDATE CATALYST | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | claimed |
| EP-3299358-A1 | AMIDE DERIVATIVE AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2018-03-28 | — | — | EP | disclosed |
| EP-1702917-B1 | AMIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2017-08-02 | — | — | EP | disclosed |
| WO-2013149996-A9 | SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS | ALMIRALL, S.A. (ES) | 2014-02-20 | — | — | WO | disclosed |
| WO-2013149997-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS | ALMIRALL, S.A. (ES) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013149996-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS | ALMIRALL, S.A. (ES) | 2013-10-10 | — | — | WO | disclosed |
| US-7728131-B2 | 3-difluoromethyl-4-(4-methylpiperazin-1-ylmethyl)-N-{4-methyl-3-[4-(5-pyrimidinyl)pyrimidin-2-ylamino]phenyl}benzamide, having excellent tyrosine kinase inhibitory activity, used as therapeutic agent for leukemia | NIPPON SHINYAKU CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080293940-A1 | Amide Derivative and Medicine | NIPPON SHINYAKU CO., LTD. (JP) | 2008-11-27 | — | — | US | disclosed |
| US-7169325-B2 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1702917-A1 | AMIDE DERIVATIVE AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2006-09-20 | — | — | EP | disclosed |
| WO-2001083420-A2 | METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
| US-6201152-B1 | HEATING MIXTURE OF METHYL-3,5-DICHLORO-4-METHYLBENZOATE AND ALPHA,ALPHA,ALPHA-TRICHLOROMETHYLBENZENE IN PRESENCE OF AMMONIUM MOLYBDATE CATALYST | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | disclosed |
| US-6118018-A | Chlorination and bromination of aromatic compounds at atmospheric pressure | OCCIDENTAL CHEMICAL CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |
| US-5886210-A | Method for preparing aromatic compounds | ROHM AND HAAS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0825173-A1 | Method for preparing aromatic compounds | ROHM AND HAAS COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293940-A1 | Amide Derivative and Medicine | ABL2, ABL1, BCR | CA1 4727/4885CA2 1951/4885CA12 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.