SCHEMBL27733409

SCHEMBL27733409

CC(C)CCc1cc(O)ccc1/C=C/C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.51
APP P05067 1/20 0.40
TYR P14679 4/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA4 P22748 3/20 0.40
CA12 O43570 2/20 0.40
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
ESR1 P03372 2/20 0.40
AKR1B10 O60218 2/20 0.40
AKR1B1 P15121 2/20 0.40
BACE1 P56817 1/20 0.40
CA3 P07451 1/20 0.40
PKM P14618 1/20 0.40
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27733413 1.00 MIF (0.51) MIFAPPTYRCA1CA2
SCHEMBL196086 0.82 PTGER4 (0.48) CA1CA2CA4CA12CA6
SCHEMBL10891531 0.82 PTGS2 (0.41) MIFCA1CA2CA4CA12
SCHEMBL290383 0.82 PTGER4 (0.48) CA1CA2CA4CA12CA6
SCHEMBL9447849 0.82 MIF (0.60) MIFAPPTYRCA1CA2
SCHEMBL10350184 0.82 MIF (0.60) MIFAPPTYRCA1CA2
SCHEMBL7937596 0.81 MIF (0.53) MIFAPPTYRCA1CA2
SCHEMBL7937601 0.81 MIF (0.53) MIFAPPTYRCA1CA2
SCHEMBL1716808 0.81 PTGER3 (0.54) CA1CA2CA4HCAR2NFKB1
SCHEMBL3928418 0.81 MIF (0.59) MIFAPPTYRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101365493-A Keratin-binding effector molecules, and method for the production thereof BASF AG (DE) 2009-02-11 CN disclosed