SCHEMBL196086

SCHEMBL196086

COc1ccc(/C=C/C(=O)O)c(CCC(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.48
PTGER3 P43115 1/20 0.48
PTGER2 P43116 1/20 0.48
THRB P10828 1/20 0.47
ATM Q13315 1/20 0.47
MAPT P10636 4/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GAA P10253 1/20 0.45
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LY96 Q9Y6Y9 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290383 1.00 PTGER4 (0.48) PTGER4PTGER3PTGER2THRBATM
4-Methoxycinnamic Acid SCHEMBL19717829 0.94 THRB (0.58) PTGER4PTGER3PTGER2THRBATM
Coumarinic Acid Methyl Ether SCHEMBL19717828 0.91 GAA (0.55) PTGER4PTGER3PTGER2MAPTALDH1A1
SCHEMBL2834265 0.87 ALDH1A1 (0.50) PTGER4PTGER3PTGER2MAPTALDH1A1
SCHEMBL2834266 0.87 ALDH1A1 (0.50) PTGER4PTGER3PTGER2MAPTALDH1A1
Amiloxate SCHEMBL23114206 0.86 LMNA (0.69) PTGER4PTGER3PTGER2THRBATM
SCHEMBL489473 0.85 PTGER4 (0.51) PTGER4PTGER3PTGER2THRBATM
SCHEMBL489472 0.85 PTGER4 (0.51) PTGER4PTGER3PTGER2THRBATM
SCHEMBL285247 0.83 PTGER4 (0.54) PTGER4PTGER3PTGER2THRBATM
SCHEMBL285246 0.83 PTGER4 (0.54) PTGER4PTGER3PTGER2THRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
US-20260108435-A1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS SAES GETTERS S.P.A. (IT) 2026-04-23 US claimed
US-20260108436-A1 SUNSCREEN COMPOSITION WITH SPF BOOSTERS SAES GETTERS S.P.A. (IT) 2026-04-23 US claimed
EP-4518849-B1 COMPOSITION FOR TOPICAL APPLICATION FOR THE PHOTOTHERAPEUTIC TREATMENT OF INFLAMMATORY-BASED SKIN DISEASES GIULIANI SPA (IT) 2026-04-08 EP claimed
EP-4648735-B1 SUNSCREEN COMPOSITION WITH SPF BOOSTERS GETTERS SPA (IT) 2026-03-11 EP claimed
EP-4706780-A2 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2026-03-11 EP claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
EP-4648734-B1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS GETTERS SPA (IT) 2026-02-18 EP claimed
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof EVOLVED BY NATURE INC (US) 2026-01-15 US claimed
EP-4251121-B1 TOPICAL COMPOSITION DSM IP ASSETS BV (NL) 2025-10-01 EP claimed
US-6235271-B1 A SUNSCREEN AGENT COMPRISING A MICRONIZED ORGANIC ULTRAVIOLET ABSORBER, AN OIL SOLUBLE, NON-MICRONIZED ULTRAVIOLET ABSORBER AND/OR INORGANIC MICROPIGMENT AND A COPOLYMER OF ACRYLIC ACID-STYRENE AS HOLLOW SPHERE CIBA SPECIALTY CHEMICALS CORPORATION 2001-05-22 US claimed
WO-2001003663-A1 SUNSCREEN FORMULATIONS H A MILTON HOLDINGS PTY LTD (AU) 2001-01-18 WO claimed
EP-0969004-A2 2,4,6-Trianilino-1,3,5-triazine derivatives, their preparation and their use as sunscreens against UV-B sun radiations 3V SIGMA S.p.A (IT) 2000-01-05 EP claimed
EP-0893119-A1 UV-protection formulation Ciba SC Holding AG (CH) 1999-01-27 EP claimed
EP-0834302-A1 Compositions comprising glutathione liposomes Boehringer Ingelheim Limited (GB) 1998-04-08 EP claimed
EP-0419164-B1 Hair conditioning composition UNILEVER PLC (GB) 1994-11-30 EP claimed
EP-0386898-B1 SHAMPOO COMPOSITION UNILEVER PLC (GB) 1993-09-01 EP claimed
US-5186928-A Anionic surfactant, water-insoluble sunscreen, and cationic derivative of polygalactomannan gum CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-02-16 US claimed
EP-0419164-A1 Hair conditioning composition UNILEVER PLC (GB) 1991-03-27 EP claimed
EP-0386898-A1 Shampoo composition UNILEVER PLC (GB) 1990-09-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108435-A1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS SOD1, MCM5, GSTM1 PTGER4 1475/4885PTGER3 1832/4885PTGER2 2043/4885
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof CUTA, CD44, F12 PTGER4 1772/4885PTGER3 1893/4885PTGER2 835/4885
US-20260108436-A1 SUNSCREEN COMPOSITION WITH SPF BOOSTERS BRCA1, SQOR, NDUFB5 PTGER4 746/4885PTGER3 995/4885PTGER2 564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.