SCHEMBL7937596

SCHEMBL7937596

CCCCc1cc(O)ccc1/C=C/C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.53
TYR P14679 3/20 0.49
ESR1 P03372 6/20 0.46
ESR2 Q92731 5/20 0.46
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.45
ERAP1 Q9NZ08 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX5 P09917 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTGER4 P35408 2/20 0.42
PTGER3 P43115 2/20 0.42
PTGER2 P43116 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937601 1.00 MIF (0.53) MIFTYRESR1ESR2ALDH1A1
SCHEMBL2495105 0.96 MIF (0.51) MIFTYRESR1ESR2MEN1
SCHEMBL2495109 0.96 MIF (0.51) MIFTYRESR1ESR2MEN1
SCHEMBL10705517 0.94 TDP1 (0.51) MIFTYRESR1ESR2MEN1
SCHEMBL10705521 0.94 TDP1 (0.51) MIFTYRESR1ESR2MEN1
SCHEMBL9447849 0.86 MIF (0.60) MIFTYRESR1ESR2ALDH1A1
SCHEMBL10350184 0.86 MIF (0.60) MIFTYRESR1ESR2ALDH1A1
SCHEMBL28552435 0.85 ATG4B (0.48) ALDH1A1TDP1PTGER4PTGER3PTGER2
SCHEMBL6367458 0.84 TDO2 (0.46) MIFESR1ESR2ALDH1A1GAA
SCHEMBL1322604 0.83 ESR1 (0.43) ESR1ESR2ALDH1A1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014105405-A1 ANTIOXIDANTS FOR USE IN SOLVENT EXTRACTION SYSTEMS FLSMIDTH A/S (DK) 2014-07-03 WO disclosed
EP-1124891-A1 POLYETHERIMIDE RESIN/POLYESTER RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2001-08-22 EP disclosed
WO-2000012604-A1 POLYETHERIMIDE RESIN/POLYESTER RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-03-09 WO disclosed
EP-0372728-A2 Smoothly removable cover tape for electronic component carrier MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-13 EP disclosed
EP-0076996-B1 CARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM Roche Diagnostics GmbH (DE) 1986-01-02 EP disclosed
US-3953398-A 3,5-DI-TERT-ALKYL-4-HYDROXYCINNAMIC ACID OR ESTER AS STABILIZER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-27 US disclosed