Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248698 | 0.76 | MTNR1A (0.38) | MTNR1ASMYD3ESR1ESR2ADRA1A | |
| SCHEMBL14012390 | 0.74 | ALDH1A1 (0.42) | NOS3NOS2MTNR1ASMYD3ESR1 | |
| SCHEMBL16037063 | 0.74 | DDB1 (0.41) | MTNR1ASMYD3ESR1ESR2ADRA1A | |
| SCHEMBL29746175 | 0.74 | DDB1 (0.41) | MTNR1ASMYD3ESR1ESR2ADRA1A | |
| SCHEMBL16687109 | 0.72 | MEN1 (0.35) | NOS3NOS2MTNR1ASMYD3HTR1A | |
| SCHEMBL13784817 | 0.71 | ESR1 (0.51) | MTNR1ASMYD3ESR1ESR2KDM4E | |
| SCHEMBL13306192 | 0.71 | ESR1 (0.51) | MTNR1ASMYD3ESR1ESR2KDM4E | |
| SCHEMBL30124970 | 0.71 | ESR1 (0.51) | MTNR1ASMYD3ESR1ESR2KDM4E | |
| SCHEMBL5051433 | 0.71 | ESR1 (0.51) | MTNR1ASMYD3ESR1ESR2KDM4E | |
| SCHEMBL16590096 | 0.70 | ESR1 (0.41) | MTNR1ASMYD3ESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101233132-A | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC (US) | 2008-07-30 | — | — | CN | disclosed |