Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753899 | 0.85 | TAAR1 (0.38) | TAAR1CYP19A1F2RL1ADRA1AHTR1A | |
| SCHEMBL706070 | 0.82 | CYP19A1 (0.48) | TAAR1CYP19A1F2RL1ADRA1AADRA2A | |
| SCHEMBL6299558 | 0.82 | CYP19A1 (0.46) | TAAR1CYP19A1F2RL1ADRA1AADRA2A | |
| SCHEMBL698787 | 0.81 | CYP19A1 (0.43) | TAAR1CYP19A1F2RL1ADRA1AADRA2A | |
| SCHEMBL698375 | 0.78 | CYP19A1 (0.40) | TAAR1CYP19A1F2RL1ADRA1AADRA2A | |
| SCHEMBL28775053 | 0.77 | CYP19A1 (0.40) | CYP19A1MDM2 | |
| SCHEMBL699180 | 0.76 | CYP19A1 (0.47) | TAAR1CYP19A1F2RL1ADRA1AADRA2A | |
| SCHEMBL697435 | 0.75 | CYP19A1 (0.46) | TAAR1CYP19A1ADRA1AADRA2AADRA2C | |
| SCHEMBL21483569 | 0.74 | TAAR1 (0.44) | TAAR1ADRA1AADRA2AADRA2CADRA1D | |
| SCHEMBL697775 | 0.74 | TAAR1 (0.44) | TAAR1CYP19A1KMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |