Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299558 | 0.88 | CYP19A1 (0.46) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL699180 | 0.87 | CYP19A1 (0.47) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL698787 | 0.87 | CYP19A1 (0.43) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL697435 | 0.86 | CYP19A1 (0.46) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL698375 | 0.83 | CYP19A1 (0.40) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL27733481 | 0.82 | TAAR1 (0.43) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL697775 | 0.79 | TAAR1 (0.44) | CYP19A1TAAR1KMT2ACYP3A4TSHR | |
| SCHEMBL1573354 | 0.78 | TAAR1 (0.40) | CYP19A1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL7914818 | 0.77 | CYP19A1 (0.51) | CYP19A1TAAR1KMT2AMDM2PDK1 | |
| SCHEMBL697917 | 0.77 | CYP19A1 (0.38) | CYP19A1TAAR1F2RL1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |