Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 12/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753970 | 0.85 | CYP19A1 (0.46) | CYP19A1MDM2F2RL1 | |
| SCHEMBL697864 | 0.82 | CYP19A1 (0.48) | CYP19A1MDM2F2RL1MAP3K14 | |
| SCHEMBL27753898 | 0.82 | CYP19A1 (0.46) | CYP19A1MDM2F2RL1 | |
| SCHEMBL27733475 | 0.76 | CYP19A1 (0.38) | CYP19A1MDM2 | |
| SCHEMBL5924568 | 0.76 | CYP19A1 (0.49) | CYP19A1MDM2F2RL1 | |
| SCHEMBL28778575 | 0.75 | CYP19A1 (0.35) | CYP19A1MDM2F2RL1 | |
| SCHEMBL697313 | 0.74 | CYP19A1 (0.41) | CYP19A1MDM2F2RL1 | |
| SCHEMBL697276 | 0.73 | CYP19A1 (0.41) | CYP19A1MDM2F2RL1MAP3K14 | |
| SCHEMBL697452 | 0.73 | CYP19A1 (0.49) | CYP19A1MDM2 | |
| SCHEMBL698661 | 0.72 | CYP19A1 (0.53) | CYP19A1MDM2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |