Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924568 | 0.87 | CYP19A1 (0.49) | CYP19A1MEN1KMT2AMDM2 | |
| SCHEMBL697304 | 0.85 | CYP19A1 (0.50) | CYP19A1NISCHMEN1KMT2ATAAR1 | |
| SCHEMBL697534 | 0.84 | CYP19A1 (0.41) | CYP19A1MEN1KMT2ATAAR1CES2 | |
| SCHEMBL6302051 | 0.83 | CYP19A1 (0.47) | CYP19A1NISCHMEN1KMT2ATAAR1 | |
| SCHEMBL697087 | 0.83 | CYP19A1 (0.47) | CYP19A1NISCHMEN1KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL11532663 | 0.81 | CYP19A1 (0.68) | CYP19A1FPR2AHRKIF11NISCH | |
| SCHEMBL11670362 | 0.79 | CYP19A1 (0.42) | CYP19A1FPR2MDM2 | |
| SCHEMBL697864 | 0.78 | CYP19A1 (0.48) | CYP19A1MDM2GSK3AGSK3B | |
| SCHEMBL697775 | 0.78 | TAAR1 (0.44) | CYP19A1NISCHMEN1KMT2ATAAR1 | |
| SCHEMBL11533232 | 0.78 | CYP19A1 (0.62) | CYP19A1FPR2AHRKIF11NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |