Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312243 | 0.82 | GPR84 (0.56) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL6686403 | 0.82 | CES2 (0.51) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL6684015 | 0.82 | CES2 (0.51) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL8901194 | 0.82 | CES2 (0.51) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL6683969 | 0.82 | CES2 (0.51) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL2563963 | 0.82 | GPR84 (0.56) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL15659882 | 0.82 | CES2 (0.51) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL1195165 | 0.82 | CES2 (0.51) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL7633629 | 0.82 | GPR84 (0.56) | MMP2MMP9MMP12CES2CES1 | |
| SCHEMBL12475412 | 0.82 | PGR (0.49) | MMP2MMP9MMP12CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015606-B | IRE-1 alpha inhibitors | MANNKIND CORP | 2015-02-04 | — | — | CN | disclosed |
| CN-103450077-A | IRE-1A inhibitors | MANNKIND CORP | 2013-12-18 | — | — | CN | disclosed |
| CN-101326148-B | A novel process for the manufacture of 5-nonyl salicylaldoxime | STAR ORECHEM INTERNAT PVT LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-101326148-A | A novel process for the manufacture of 5-nonyl salicylaldoxime | STAR ORECHEM INTERNAT PVT LTD (IN) | 2008-12-17 | — | — | CN | disclosed |