Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 8/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733811 | 0.91 | DYRK1A (0.49) | DYRK1AACP1CSNK1DAKT1MTOR | |
| SCHEMBL27733759 | 0.89 | DYRK1A (0.49) | DYRK1AACP1AKT1PDPK1NPC1 | |
| SCHEMBL27733656 | 0.88 | PPARG (0.36) | DYRK1AACP1CSNK1DNPC1RAB9A | |
| SCHEMBL27713321 | 0.88 | SCN4A (0.42) | DYRK1AACP1CSNK1DNPC1RAB9A | |
| SCHEMBL28775101 | 0.84 | PPARG (0.43) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL27713303 | 0.82 | POLB (0.36) | DYRK1ANPC1RAB9APOLB | |
| SCHEMBL27733879 | 0.79 | DYRK1A (0.47) | DYRK1AACP1AKT1PDPK1NPC1 | |
| SCHEMBL27713459 | 0.79 | PPARG (0.36) | DYRK1AACP1CSNK1DRAB9AMEN1 | |
| SCHEMBL27733828 | 0.76 | PPARG (0.47) | NPC1RAB9AKMT2APIK3CG | |
| SCHEMBL28775092 | 0.76 | AKR1C3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |