Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733759 | 0.90 | DYRK1A (0.49) | DYRK1AFSCN1ACP1MAPTRAB9A | |
| SCHEMBL27733811 | 0.89 | DYRK1A (0.49) | DYRK1AACP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27733680 | 0.88 | PPARG (0.47) | MAPTRAB9AP2RX3CASP3SENP8 | |
| SCHEMBL28775098 | 0.88 | PPARG (0.47) | ACP1MAPTRAB9AP2RX3PIK3CG | |
| SCHEMBL27733702 | 0.84 | PPARG (0.46) | RAB9AP2RX3NPC1POLBPPARG | |
| SCHEMBL27733859 | 0.82 | PPARA (0.47) | RAB9ANPC1SMN1; SMN2TP53PPARG | |
| SCHEMBL27733852 | 0.80 | PSEN1 (0.39) | POLBPPARGPPARD | |
| SCHEMBL27733706 | 0.79 | DYRK1A (0.52) | DYRK1AFSCN1ACP1RAB9APIK3CG | |
| SCHEMBL27733711 | 0.79 | PPARG (0.41) | PPARGPPARD | |
| SCHEMBL27733863 | 0.79 | PPARG (0.47) | MAPTPIK3CGLMNACYP1A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |