Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733706 | 0.91 | DYRK1A (0.52) | DYRK1AACP1CSNK1DAKT1MTOR | |
| SCHEMBL27733879 | 0.89 | DYRK1A (0.47) | DYRK1AACP1AKT1RAB9ANPC1 | |
| SCHEMBL27713459 | 0.89 | PPARG (0.36) | DYRK1AACP1CSNK1DRAB9A | |
| SCHEMBL28775099 | 0.84 | PPARG (0.43) | RAB9ANPC1 | |
| SCHEMBL27713509 | 0.83 | AKR1B1 (0.36) | DYRK1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27713592 | 0.80 | ALDH1A1 (0.36) | SMN1; SMN2 | |
| SCHEMBL27733759 | 0.79 | DYRK1A (0.49) | DYRK1AACP1AKT1RAB9ANPC1 | |
| SCHEMBL27733656 | 0.79 | PPARG (0.36) | DYRK1AACP1CSNK1DRAB9ANPC1 | |
| SCHEMBL27833814 | 0.79 | PPARG (0.37) | SMN1; SMN2 | |
| SCHEMBL27713321 | 0.78 | SCN4A (0.42) | DYRK1AACP1CSNK1DRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |