Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18248667 | 0.99 | SFRP1 (0.98) | SFRP1WNT3 | |
| SCHEMBL6102423 | 0.93 | SFRP1 (0.88) | SFRP1WNT3 | |
| SCHEMBL4618643 | 0.93 | SFRP1 (0.88) | SFRP1WNT3 | |
| SCHEMBL6102796 | 0.93 | SFRP1 (0.88) | SFRP1WNT3 | |
| SCHEMBL4736328 | 0.91 | SFRP1 (0.83) | SFRP1WNT3 | |
| SCHEMBL4618189 | 0.89 | SFRP1 (0.80) | SFRP1WNT3 | |
| SCHEMBL6102189 | 0.88 | SFRP1 (0.78) | SFRP1WNT3 | |
| SCHEMBL6102520 | 0.87 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL4618085 | 0.87 | SFRP1 (0.77) | SFRP1WNT3 | |
| SCHEMBL4616557 | 0.87 | SFRP1 (0.77) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139320-A1 | StarTrace: A Multiplex Drug Testing Platform for Personalized Medicine | UNIV OF SOUTH CAROLINA (US) | 2026-05-21 | — | — | US | claimed |
| US-12577530-B2 | Generation of a population of hindbrain cells and hindbrain-like organoids from pluripotent stem cells | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2026-03-17 | — | — | US | claimed |
| EP-4680969-A1 | CANCER STRATIFICATION AND TREATMENT | Deutsches Krebsforschungszentrum (DE) | 2026-01-21 | — | — | EP | claimed |
| US-20260002134-A1 | CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2026-01-01 | — | — | US | claimed |
| US-20250376659-A1 | DERIVATION OF SOMATOTROPHS FROM STEM CELLS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-12-11 | — | — | US | claimed |
| US-12428622-B2 | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-09-30 | — | — | US | claimed |
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| US-20250241964-A1 | SCALABLE METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIUM (RPE) CELLS | EYESTEM RESEARCH PRIVATE LIMITED (IN) | 2025-07-31 | — | — | US | claimed |
| CN-120019141-A | Scalable method for generating Retinal Pigment Epithelial (RPE) cells | 艾视泰研究私人有限公司 | 2025-05-16 | — | — | CN | claimed |
| US-12297457-B2 | Esophageal tissue and/or organoid compositions and methods of making same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-05-13 | — | — | US | claimed |
| EP-4106815-A1 | METHOD FOR TREATING ASTHMA OR ALLERGIC DISEASE | The Children's Medical Center Corporation (US) | 2022-12-28 | — | — | EP | claimed |
| WO-2022226337-A1 | METHOD FOR PRODUCING HEMATOPOIETIC CELLS FROM STEM CELLS USING VASCULAR ORGANOIDS | Artec Biotech, Inc. (US) | 2022-10-27 | — | — | WO | claimed |
| US-11459547-B2 | Method for producing osteoblast cluster using human iPS cells | TOHOKU UNIVERSITY (JP) | 2022-10-04 | — | — | US | claimed |
| CN-113181428-B | Preparation method of spinal cord injury repair material and tissue engineering scaffold | 右江民族医学院附属医院 | 2022-07-22 | — | — | CN | claimed |
| US-20220145255-A1 | METHOD FOR PRODUCING OSTEOBLAST CLUSTER USING IPS CELLS | TOHOKU UNIVERSITY (JP) | 2022-05-12 | — | — | US | claimed |
| US-20220106571-A1 | CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-04-07 | — | — | US | claimed |
| WO-2022020967-A1 | USE OF WNT/BETA-CATENIN PATHWAY INHIBITORS TO BLOCK REPLICATION OF SARS-COV-2 AND OTHER PATHOGENIC VIRUSES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-02-03 | — | — | WO | claimed |
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577530-B2 | Generation of a population of hindbrain cells and hindbrain-like organoids from pluripotent stem cells | SHH, SMO, WNT3A | SFRP1 110/4885WNT3 12/4885 |
| US-20260139320-A1 | StarTrace: A Multiplex Drug Testing Platform for Personalized Medicine | PTH1R, SSTR4, MC4R | SFRP1 356/4885WNT3 494/4885 |
| US-20260002134-A1 | CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF | BMP4, WNT3A, BMP1 | SFRP1 12/4885WNT3 16/4885 |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | SFRP1, SOS1, FZD7 | SFRP1 1/4885WNT3 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.