Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 12/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587054 | 0.85 | GABRA2 (0.58) | GABRA2GABRB2 | |
| SCHEMBL3592562 | 0.82 | CNR1 (0.53) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL3583597 | 0.78 | RXRA (0.46) | — | |
| SCHEMBL19365969 | 0.78 | BRD4 (0.40) | PPARAMCL1KMT2A | |
| SCHEMBL15459665 | 0.76 | CNR1 (0.50) | GABRA2GABRB2CNR1CNR2MEN1 | |
| SCHEMBL3583946 | 0.74 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL27915507 | 0.73 | CCKAR (0.41) | GABRA2GABRB2CNR1RXFP1MCL1 | |
| SCHEMBL4516659 | 0.73 | CNR1 (0.57) | GABRA2GABRB2CNR1CNR2 | |
| SCHEMBL6335073 | 0.72 | CNR1 (0.64) | GABRA2GABRB2CNR1CNR2 | |
| SCHEMBL5440875 | 0.72 | CNR1 (0.55) | GABRA2GABRB2CNR1RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248049-B | Imidazole based lxr modulators | EXELIXIS INC | 2013-08-28 | — | — | CN | disclosed |
| CN-101248049-A | Imidazole based LXR modulators | EXELIXIS INC (US) | 2008-08-20 | — | — | CN | disclosed |