Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428128 | 0.84 | HTR6 (0.68) | HTR6POLBL3MBTL1PPARGHDAC3 | |
| Ethoxycarbonyl Group SCHEMBL28823657 | 0.79 | HTR6 (0.55) | HTR6POLBL3MBTL1PPARGHDAC3 | |
| SCHEMBL947751 | 0.77 | HTR6 (0.63) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL27733954 | 0.77 | ITGB3 (0.37) | HTR6PPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL28770820 | 0.77 | GRIK1 (0.39) | HTR6POLBL3MBTL1PPARGHDAC3 | |
| SCHEMBL27713413 | 0.76 | SMPD2 (0.42) | HTR6PPARGPPARAPPARD | |
| SCHEMBL19268814 | 0.76 | HTR6 (0.66) | HTR6POLBL3MBTL1HDAC3HDAC4 | |
| SCHEMBL27733854 | 0.75 | HTR6 (0.38) | HTR6POLBPPARGHDAC3HDAC4 | |
| SCHEMBL19181960 | 0.74 | HTR6 (0.47) | HTR6POLBL3MBTL1PPARGHDAC3 | |
| SCHEMBL27833770 | 0.74 | PPARG (0.35) | HTR6PPARGHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |