Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733849 | 0.89 | PPARG (0.36) | FABP4P2RX3PPARGPPARDPPARA | |
| SCHEMBL27733824 | 0.88 | TRPV1 (0.37) | FABP4PTGS1PTGS2PPARGPPARA | |
| SCHEMBL27733784 | 0.84 | PSEN1 (0.42) | PTGS1PTGS2PSEN1PSEN2APH1B | |
| SCHEMBL27713457 | 0.84 | PSEN1 (0.46) | FABP4PTGS1PTGS2PSEN1PSEN2 | |
| SCHEMBL27733705 | 0.83 | PSEN1 (0.34) | PTGS1PTGS2PSEN1PSEN2APH1B | |
| SCHEMBL27733655 | 0.82 | NOTUM (0.47) | MAPT | |
| SCHEMBL28775103 | 0.82 | MEN1 (0.41) | PPARGPPARDPPARAPSEN1PSEN2 | |
| SCHEMBL27713686 | 0.81 | PPARG (0.41) | PPARGPPARDPPARAPSEN1PSEN2 | |
| SCHEMBL27713338 | 0.81 | PSEN1 (0.40) | PTGS1PTGS2PSEN1PSEN2APH1B | |
| SCHEMBL28770821 | 0.80 | PTGS2 (0.39) | PTGS2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |