Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733696 | 0.91 | PTGS1 (0.40) | PPARGPPARDPPARAMAPTGCGR | |
| SCHEMBL27733800 | 0.89 | FABP4 (0.40) | PPARGPPARDPPARAP2RX3HSD11B1 | |
| SCHEMBL28775106 | 0.88 | TRPV1 (0.34) | PPARGPPARDPPARAHDAC3HDAC4 | |
| SCHEMBL27733699 | 0.88 | DAGLA (0.35) | PPARGPPARDPPARAMAPTPKM | |
| SCHEMBL28770838 | 0.84 | ALDH1A1 (0.35) | PPARGPPARDPPARAMAPT | |
| SCHEMBL27733852 | 0.84 | PSEN1 (0.39) | PPARGPPARDPPARAFABP4 | |
| SCHEMBL27713300 | 0.83 | NOTUM (0.45) | MAPT | |
| SCHEMBL27733711 | 0.82 | PPARG (0.41) | PPARGPPARDPPARA | |
| SCHEMBL27833766 | 0.81 | PHGDH (0.38) | PPARGPPARDPPARA | |
| SCHEMBL27733841 | 0.79 | F7 (0.36) | PPARGPPARDPPARAP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |