Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713453 | 0.94 | AKR1B1 (0.34) | TP53MAPTPPARDPPARGPPARA | |
| SCHEMBL28775095 | 0.89 | DYRK1A (0.48) | ACP1ALDH1A1DYRK1ACSNK1DSMN1; SMN2 | |
| SCHEMBL28943735 | 0.89 | PPARG (0.41) | TP53MAPTMEN1CYP2C9KMT2A | |
| SCHEMBL27733685 | 0.88 | PPARG (0.37) | MEN1KMT2APPARDPPARGPPARA | |
| SCHEMBL28770874 | 0.85 | ALDH1A1 (0.35) | PPARDPPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL27713348 | 0.82 | PPARA (0.41) | PPARDPPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL27910315 | 0.81 | HTR6 (0.37) | CYP2C9PPARG | |
| SCHEMBL28791617 | 0.81 | HTR6 (0.35) | MEN1CYP2C9KMT2APPARDPPARG | |
| SCHEMBL27713347 | 0.81 | TRPM8 (0.38) | MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL28775085 | 0.80 | PPARG (0.41) | CYP2C9KMT2APPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |