Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773405 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL21650396 | 0.73 | KDM4E (0.37) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL31567982 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27552127 | 0.71 | PDE7A (0.34) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7258318 | 0.70 | HTR6 (0.34) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9055286 | 0.70 | HTT (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7263603 | 0.70 | SIRT1 (0.40) | HSD17B10 | |
| SCHEMBL18540921 | 0.65 | ACHE (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL21650388 | 0.65 | ACHE (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL14218716 | 0.65 | KDM4E (0.35) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465506-A | Herbicidal N-[heterocyclicaminocarbonyl]-1H-indene and tetrahydronaphthalene sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0082681-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |