Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734340 | 0.92 | MEN1 (0.51) | MEN1CYP1A2KMT2ASRD5A2MAPT | |
| SCHEMBL1824580 | 0.86 | CYP3A4 (0.38) | LMNAALDH1A1CA1CA2MAPK1 | |
| SCHEMBL1823948 | 0.80 | CA2 (0.35) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL1827773 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3503452 | 0.77 | SRD5A2 (0.44) | MEN1CYP1A2KMT2ASRD5A2MAPT | |
| SCHEMBL27521467 | 0.76 | SRD5A2 (0.49) | MEN1CYP1A2KMT2ASRD5A2MAPT | |
| SCHEMBL1020012 | 0.76 | SRD5A2 (0.49) | MEN1CYP1A2KMT2ASRD5A2MAPT | |
| SCHEMBL1147825 | 0.75 | CA1 (0.44) | MEN1KMT2AMAPTNR1H4EPHX2 | |
| SCHEMBL27477488 | 0.75 | EPHX2 (0.37) | MEN1CYP1A2KMT2AMAPTEPHX2 | |
| SCHEMBL3525214 | 0.74 | ESR1 (0.44) | MEN1CYP1A2KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296904-A | Amide derivatives as kinase inhibitors | DEVGEN NV (BE) | 2008-10-29 | — | — | CN | disclosed |
| CN-101248046-A | Amide derivatives as kinase inhibitors | DEVGEN NV (BE) | 2008-08-20 | — | — | CN | disclosed |