Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | PPIG | Q13427 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824580 | 0.77 | CYP3A4 (0.38) | ESRRGDGAT1ALDH1A1HPGDMAPK1 | |
| SCHEMBL27734340 | 0.77 | MEN1 (0.51) | EPHX2MAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL27734342 | 0.75 | MEN1 (0.49) | EPHX2MAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL27644513 | 0.74 | CYP1A2 (0.43) | NPC1MAPTRAB9ACACNA1BMEN1 | |
| SCHEMBL3568477 | 0.73 | CA1 (0.37) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17825682 | 0.73 | CYP2C19 (0.47) | MAPTKCNN4MEN1CYP1A2KMT2A | |
| SCHEMBL2795231 | 0.72 | MIF (0.42) | MAPTMEN1CYP1A2KMT2A | |
| SCHEMBL23094097 | 0.72 | MAPT (0.47) | MAPTKCNN4CYP1A2KMT2A | |
| SCHEMBL1823948 | 0.71 | CA2 (0.35) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8395320 | 0.71 | DGAT1 (0.47) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1310169-A | Anils with nitric oxide synzyme inhibiting function | SHUGAI SEIYAKU K K (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1172473-A | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |