SCHEMBL27734367

SCHEMBL27734367

Cc1ccccc1Oc1ccc(N)cc1N

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.47
SLC6A4 P31645 3/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
TSHR P16473 1/20 0.44
RAB9A P51151 1/20 0.44
AR P10275 2/20 0.44
ALDH1A1 P00352 4/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
CASP7 P55210 1/20 0.43
ATM Q13315 1/20 0.43
SLC6A2 P23975 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5552568 0.89 SMN1; SMN2 (0.47) CASP1SLC6A4MEN1KMT2ASMN1; SMN2
SCHEMBL5707641 0.86 ALDH1A1 (0.46) CASP1SLC6A4MEN1KMT2ASMN1; SMN2
SCHEMBL28248142 0.84 CASP1 (0.42) CASP1SLC6A4MEN1KMT2ATSHR
SCHEMBL599354 0.84 GAA (0.50) CASP1SLC6A4MEN1KMT2ASMN1; SMN2
SCHEMBL27746114 0.83 ALDH1A1 (0.44) CASP1SLC6A4MEN1KMT2ATSHR
SCHEMBL29549546 0.82 ALDH1A1 (0.48) CASP1SLC6A4MEN1KMT2ASMN1; SMN2
SCHEMBL25500740 0.82 AR (0.60) SLC6A4MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL21191204 0.82 ALDH1A1 (0.42) SLC6A4MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL1583991 0.82 AR (0.42) SLC6A4MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29597724 0.82 ALDH1A1 (0.54) CASP1SLC6A4MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 CN claimed
CN-106479178-A A kind of 6FDA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-03-08 CN claimed
CN-106479183-A A kind of HQDA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-03-08 CN claimed
CN-106479177-A A kind of BPADA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-03-08 CN claimed
CN-106398211-A PMDA type BDATHQ branched polyimide resin film and production method thereof 东华大学 2017-02-15 CN claimed
CN-106280452-A A kind of BPDA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-01-04 CN claimed
CN-106277929-A A kind of BDATHQ type granolith sheet material and preparation method thereof 东华大学 2017-01-04 CN claimed
CN-106243353-A A kind of BDATHQ type siliceous epoxy acid imide matrix resin and preparation method thereof 东华大学 2016-12-21 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN disclosed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 CN disclosed
CN-106751488-B A kind of preparation method of crystal waste slag/BDATHQ type epoxy matrix resin composite materials 东华大学 2019-01-15 CN disclosed
CN-106479177-A A kind of BPADA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-03-08 CN disclosed
CN-106479183-A A kind of HQDA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-03-08 CN disclosed
CN-106280452-A A kind of BPDA type BDATHQ branched polyimide resin film and preparation method thereof 东华大学 2017-01-04 CN disclosed
CN-103254573-B A kind of High-temperature-resmicant micant plate matrix resin and preparation method thereof 东华大学 2016-08-10 CN disclosed
CN-103131372-B 2,6-bis(2,4-diamidophenoxy)toluene high-temperature-resistant epoxy adhesive and preparation method thereof NAT UNIV DONG HWA 2014-12-10 CN disclosed
CN-103131372-A 2,6-bis(2,4-diamidophenoxy)toluene high-temperature-resistant epoxy adhesive and preparation method thereof UNIV DONGHUA 2013-06-05 CN disclosed
CN-101250124-A Method for preparing 2,5-di(2,4-diamino phenoxy) toluene UNIV DONGHUA (CN) 2008-08-27 CN disclosed
CN-101250123-A Method for preparing 2,4-di(2,4-diamino phenoxy) toluene UNIV DONGHUA (CN) 2008-08-27 CN disclosed