SCHEMBL5707641

SCHEMBL5707641

Nc1ccc(Oc2ccccc2Oc2ccc(N)cc2N)c(N)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
MAPT P10636 4/20 0.46
CYP3A4 P08684 4/20 0.46
GAA P10253 3/20 0.46
KDM4E B2RXH2 3/20 0.46
CASP1 P29466 3/20 0.46
HTT P42858 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CASP7 P55210 2/20 0.46
TP53 P04637 2/20 0.46
USP2 O75604 1/20 0.46
POLB P06746 1/20 0.46
ATM Q13315 1/20 0.46
SLC6A4 P31645 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599354 0.93 GAA (0.50) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL30462573 0.91 ALDH1A1 (0.52) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL4532343 0.91 ALDH1A1 (0.52) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL5317178 0.90 ALDH1A1 (0.50) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL13292703 0.88 TSHR (0.42) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL27734351 0.87 IDO1 (0.44) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL27734367 0.86 CASP1 (0.47) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL27737775 0.85 ALDH1A1 (0.42) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL27966664 0.85 MAPT (0.42) ALDH1A1MAPTCYP3A4GAAKDM4E
SCHEMBL27723843 0.85 ALDH1A1 (0.50) ALDH1A1MAPTCYP3A4GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
CN-110066407-A A kind of high flame-retardant resin film and preparation method thereof 东华大学 2019-07-30 CN claimed
CN-109722208-A A kind of 12BDAPB type silicon-containing adhesive and preparation method thereof 东华大学 2019-05-07 CN claimed
CN-106751497-B A kind of preparation method of crystal waste slag/BDADTBHQ type epoxy matrix resin composite materials 东华大学 2019-01-11 CN claimed
CN-103122231-B 1,4-di(2,4-diamino phenoxy) benzenoid form high-temperature epoxy adhesive and preparation method thereof UNIV DONGHUA 2014-07-02 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN disclosed
CN-110066407-A A kind of high flame-retardant resin film and preparation method thereof 东华大学 2019-07-30 CN disclosed
CN-110016138-A A kind of high flame retardant Kapton and preparation method thereof 东华大学 2019-07-16 CN disclosed
CN-109852340-A A kind of YASI-BDAPOFP type Organic fluoride silica gel and preparation method thereof 福建省海钛智能科技有限公司 2019-06-07 CN disclosed
CN-109852331-A A kind of bis- (4- amino-benzene oxygen) benzoic acid type organic silica gels of 3,5- and preparation method thereof 福建省海钛智能科技有限公司 2019-06-07 CN disclosed
CN-106751492-B A kind of preparation method of crystal waste slag/biphenyl tetramine type epoxy matrix resin composite materials 东华大学 2019-06-04 CN disclosed
CN-109735295-A A kind of acid imide organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2019-05-10 CN disclosed
EP-0918051-B1 Novel Bis-(2,4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods BRISTOL MYERS SQUIBB CO (US) 2001-09-12 EP disclosed
EP-0918051-B1 Novel Bis-(2,4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods BRISTOL MYERS SQUIBB CO (US) 2001-09-12 EP disclosed
WO-2001002492-A1 NOVEL DYES AND COLORANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-01-11 WO disclosed
EP-0918051-A1 Novel Bis-(2,4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods Bristol-Myers Squibb Company (US) 1999-05-26 EP disclosed
EP-0918051-A1 Novel Bis-(2,4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods Bristol-Myers Squibb Company (US) 1999-05-26 EP disclosed
EP-0918051-A1 Novel Bis-(2,4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods Bristol-Myers Squibb Company (US) 1999-05-26 EP disclosed
US-5865854-A HIGH INTENSITY; COLORFAST BRISTOL-MYERS SQUIBB COMPANY (US) 1999-02-02 US disclosed
US-5865854-A HIGH INTENSITY; COLORFAST BRISTOL-MYERS SQUIBB COMPANY (US) 1999-02-02 US disclosed