Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 10/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | BLM | P54132 | 5/20 | 0.66 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.66 |
| ▸ | RECQL | P46063 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.66 |
| ▸ | CASP1 | P29466 | 3/20 | 0.66 |
| ▸ | CASP7 | P55210 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079386 | 0.83 | MEN1 (0.81) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL27734202 | 0.80 | MEN1 (1.00) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL9613362 | 0.80 | PTPN7 (0.88) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL7696747 | 0.79 | TDP1 (1.00) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL15665921 | 0.79 | ALDH1A1 (0.87) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL12462566 | 0.79 | ALDH1A1 (0.66) | PIK3R1PIK3CAMEN1ALDH1A1MAPT | |
| SCHEMBL27734154 | 0.79 | ALDH1A1 (0.66) | PIK3R1PIK3CAMEN1ALDH1A1MAPT | |
| SCHEMBL6238182 | 0.77 | PIK3R1 (0.66) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL6235497 | 0.77 | PIK3R1 (0.66) | PIK3R1PIK3CAMEN1ALDH1A1POLB | |
| SCHEMBL1301829 | 0.77 | ALDH1A1 (0.68) | PIK3R1PIK3CAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101318938-B | Method for synthesizing quinoxaline derivant | UNIV SUZHOU | 2010-08-25 | — | — | CN | disclosed |
| CN-101318938-A | Method for synthesizing quinoxaline derivant | UNIV SOOCHOW (CN) | 2008-12-10 | — | — | CN | disclosed |