Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161298 | 0.84 | HCRTR1 (0.74) | KDM4EALDH1A1HPGDHCRTR1CYP19A1 | |
| SCHEMBL7348472 | 0.84 | APEX1 (0.62) | KDM4EALDH1A1THRBHPGDTBXAS1 | |
| SCHEMBL11406941 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1THRBHPGDTBXAS1 | |
| SCHEMBL10980413 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1THRBHPGDTBXAS1 | |
| SCHEMBL7080072 | 0.80 | KDM4E (0.75) | KDM4EALDH1A1THRBHPGDTBXAS1 | |
| SCHEMBL1586810 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1THRBHPGDTDP1 | |
| SCHEMBL8318727 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1THRBHPGDTBXAS1 | |
| SCHEMBL25811506 | 0.78 | KDM4E (0.67) | KDM4EALDH1A1THRBHPGDTDP1 | |
| SCHEMBL6256720 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1THRBHPGDTBXAS1 | |
| SCHEMBL10853051 | 0.76 | TBXAS1 (0.55) | KDM4EALDH1A1THRBHPGDTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384550-B | Amide derivative or salt thereof | ASTELLAS PHARMA INC | 2011-08-31 | — | — | CN | disclosed |
| CN-101384550-A | Amide derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-11 | — | — | CN | disclosed |