Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.32 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545650 | 0.79 | GRIK1 (0.39) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL31028121 | 0.77 | GRIK1 (0.38) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL1897176 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL12191191 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL16667 | 0.74 | GAPDH (0.38) | GAPDHFFAR3CMKLR1 | |
| SCHEMBL711050 | 0.74 | GAPDH (0.38) | GAPDHFFAR3CMKLR1 | |
| SCHEMBL2703569 | 0.74 | GRIK1 (0.32) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL3240320 | 0.74 | ALDH1A1 (0.39) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL17867103 | 0.72 | GAPDH (0.31) | GAPDHKISS1R | |
| SCHEMBL17867102 | 0.72 | GAPDH (0.31) | GAPDHKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136012-A | Method for preparing nanoparticles loaded with active substance | MERCK PATENT GMBH | 2014-11-05 | — | — | CN | claimed |
| CN-104136012-B | Method for preparing nanoparticles loaded with active substance | 默克专利股份有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-104136012-A | Method for preparing nanoparticles loaded with active substance | MERCK PATENT GMBH | 2014-11-05 | — | — | CN | disclosed |
| CN-103768582-A | Neuregulin capable of improving heat function when continually administrated | ZENSUN SHANGHAI SCI & TECH CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-101394861-A | Sustained administration of neuregulin can improve cardiac function | ZENSUN SHANGHAI SCIENCE & TECH (CN) | 2009-03-25 | — | — | CN | disclosed |