Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734960 | 0.79 | CHEK1 (0.35) | — | |
| SCHEMBL4135982 | 0.72 | IL6 (0.44) | LRRK2 | |
| SCHEMBL27755115 | 0.72 | — | — | |
| SCHEMBL27755097 | 0.70 | CHEK1 (0.36) | — | |
| SCHEMBL27755099 | 0.66 | CHEK1 (0.35) | — | |
| SCHEMBL27755017 | 0.65 | GRM5 (0.37) | — | |
| SCHEMBL27755194 | 0.64 | AURKA (0.30) | — | |
| SCHEMBL5038559 | 0.62 | PGR (0.51) | — | |
| SCHEMBL4132828 | 0.60 | IL6 (0.59) | LRRK2 | |
| SCHEMBL27568814 | 0.60 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400659-B | Novel 1,2,3,4-tetrahydroquinoxaline derivative having glucocorticoid receptor binding activity | SANTEN PHARMACEUTICAL CO LTD | 2012-02-29 | — | — | CN | disclosed |
| CN-101400659-A | Novel 1,2,3,4-tetrahydroquinoxaline derivative having glucocorticoid receptor binding activity | SANTEN PHARMACEUTICAL CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |