⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646793 | 0.77 | — | — | |
| SCHEMBL21889573 | 0.74 | — | — | |
| SCHEMBL2746414 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL4982209 | 0.69 | KDM4E (0.31) | — | |
| SCHEMBL2746415 | 0.69 | — | — | |
| SCHEMBL136628 | 0.67 | — | — | |
| Acetamide SCHEMBL28743112 | 0.67 | LMNA (0.50) | — | |
| SCHEMBL3439738 | 0.66 | — | — | |
| SCHEMBL21884140 | 0.66 | ALOX15 (0.41) | — | |
| Dimethyl Sulfone SCHEMBL29098852 | 0.65 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853219-B1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | BAYER AG (DE) | 2023-07-12 | — | — | EP | disclosed |
| US-20220033363-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-02-03 | — | — | US | disclosed |
| WO-2021146536-A1 | THERAPEUTIC AGENTS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-22 | — | — | WO | disclosed |
| EP-3675257-A1 | METAL FOIL, METAL FOIL PRODUCTION METHOD, SECONDARY BATTERY NEGATIVE ELECTRODE, AND SECONDARY BATTERY POSITIVE ELECTRODE | FUJIFILM Corporation (JP) | 2020-07-01 | — | — | EP | disclosed |
| WO-2020058062-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | WO | disclosed |
| EP-1581532-B1 | PYRAZOLO¬3,4-B PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2010-04-28 | — | — | EP | disclosed |
| US-7528148-B2 | Pyrazolo[3,4-B]pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LIMITED (GB) | 2009-05-05 | — | — | US | disclosed |
| US-20060252790-A1 | Pyrazolo [3,4-b] pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LIMITED (GB) | 2006-11-09 | — | — | US | disclosed |
| EP-1581532-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004056823-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |