Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449489 | 0.76 | KDM4E (0.33) | KDM4ECYP3A4CA2 | |
| SCHEMBL29202325 | 0.73 | KDM4E (0.31) | KDM4ECYP3A4CA2 | |
| SCHEMBL136628 | 0.71 | — | — | |
| SCHEMBL30640697 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL585350 | 0.71 | CA1 (0.33) | LMNA | |
| SCHEMBL570625 | 0.70 | — | — | |
| SCHEMBL14845091 | 0.69 | — | — | |
| SCHEMBL14845089 | 0.69 | — | — | |
| SCHEMBL14845088 | 0.69 | — | — | |
| Dimethyl Sulfone SCHEMBL29098852 | 0.69 | KDM4E (0.43) | KDM4ECYP3A4LMNACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310746-A1 | NEW CRYSTALLINE POLYMORPHS OF 1,6-DIBROMO-1,6-DIDEOXY-DULCITOL | Targent, LLC (US) | 2018-04-25 | — | — | EP | claimed |
| WO-2016205299-A1 | NEW CRYSTALLINE POLYMORPHS OF 1,6-DIBROMO-1,6-DIDEOXY-DULCITOL | TARGENT, LLC (US) | 2016-12-22 | — | — | WO | claimed |
| WO-2024038887-A1 | POLYMER COMPOSITION AND SINGLE-LAYER RETARDATION MATERIAL | 日産化学株式会社 | 2024-02-22 | — | — | WO | disclosed |
| US-20220296725-A1 | PYRROLOBENZODIAZEPINE ANTIBODY CONJUGATES | MERSANA THERAPEUTICS, INC. | 2022-09-22 | — | — | US | disclosed |
| EP-2970330-A1 | TETRACYCLIC BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014139324-A1 | TETRACYCLIC BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2008035315-A9 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LAB LTD (IN) | 2008-10-23 | — | — | WO | disclosed |
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2005023783-A1 | PROCESS FOR THE MANUFACTURE OF GEFITINIB | ASTRAZENECA AB (SE) | 2005-03-17 | — | — | WO | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |
| US-4874834-A | FROM AROMATIC DIAMINE AND TETRACARBOXYLIC ACID | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296725-A1 | PYRROLOBENZODIAZEPINE ANTIBODY CONJUGATES | GABRA4, GABRA1, GABRA2 | KDM4E 1256/4885CYP3A4 246/4885LMNA 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.