Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16344718 | 0.99 | GAA (0.53) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27707837 | 0.85 | GAA (0.55) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2834010 | 0.84 | GAA (0.56) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16344556 | 0.83 | GABRP (0.60) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2834608 | 0.83 | GAA (0.53) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28868306 | 0.82 | GAA (0.81) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27611112 | 0.82 | ALDH1A1 (0.41) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27611111 | 0.81 | ENPP2 (0.57) | GAAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2834061 | 0.80 | GAA (0.50) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27630087 | 0.80 | ENPP2 (0.58) | GAAL3MBTL1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |