Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923425 | 0.83 | USP47 (0.37) | GPR35RAB9AALDH1A1SMN1; SMN2GALR2 | |
| SCHEMBL4311290 | 0.81 | TSHR (0.43) | GPR35RAB9ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16737121 | 0.79 | GPR35 (0.36) | GPR35ESR2RAB9ACASP6TDP1 | |
| SCHEMBL2978000 | 0.79 | COMT (0.49) | TDP1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL11185663 | 0.77 | LMNA (0.40) | ESR2RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL10639290 | 0.71 | LMNA (0.40) | GPR35RAB9ATDP1TP53ALDH1A1 | |
| SCHEMBL5150863 | 0.70 | GPR35 (0.42) | CA1CA2GPR35TDP1TP53 | |
| SCHEMBL1845547 | 0.70 | ALDH1A1 (0.33) | ESR2RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL31028467 | 0.69 | MAPT (0.41) | RAB9ATDP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5726136 | 0.69 | LMNA (0.40) | RAB9ATDP1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331126-A | Benzimidazole thiophene compounds as PLK modulators | SMITHKLINE BEECHAM CORP (US) | 2008-12-24 | — | — | CN | disclosed |