Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735475 | 1.00 | CYP1A2 (0.39) | CYP1A2CYP3A4RECQLMAPK1PIK3CD | |
| SCHEMBL19944907 | 0.77 | PIK3CD (0.61) | CYP1A2CYP3A4RECQLMAPK1PIK3CD | |
| SCHEMBL6330224 | 0.76 | ALDH1A1 (0.46) | MAPK1 | |
| SCHEMBL28057734 | 0.74 | CYP1A2 (0.35) | CYP1A2CYP3A4RECQLMAPK1PIK3CD | |
| SCHEMBL9159698 | 0.74 | ALDH1A1 (0.33) | MAPK1PIK3CD | |
| Lithium SCHEMBL8741977 | 0.73 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL349826 | 0.72 | CYP1A2 (0.42) | CYP1A2CYP3A4RECQLMAPK1 | |
| SCHEMBL18843220 | 0.71 | CYP1A2 (0.41) | CYP1A2CYP3A4RECQLMAPK1 | |
| SCHEMBL19578354 | 0.71 | CA12 (0.33) | PIK3CD | |
| SCHEMBL12175227 | 0.71 | CA12 (0.33) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243044-A | Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | claimed |
| CN-101243044-A | Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |