Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756112 | 0.87 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL27735495 | 0.85 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL27735714 | 0.85 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL27756137 | 0.85 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL27756117 | 0.84 | MAPK14 (0.34) | HSD11B1 | |
| SCHEMBL27735497 | 0.84 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL27756122 | 0.84 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL27756131 | 0.81 | NR3C2 (0.36) | HSD11B1 | |
| SCHEMBL27756113 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL27735492 | 0.73 | POLB (0.34) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379048-B | Benzoxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP | 2012-03-21 | — | — | CN | disclosed |
| CN-101379048-A | Benzo oxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | CN | disclosed |