Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476751 | 0.80 | CALM1 (0.52) | CA1CA2CA9LTA4HMAPK1 | |
| SCHEMBL27300420 | 0.78 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL9795394 | 0.77 | TSHR (0.94) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL3216177 | 0.76 | LMNA (0.52) | ALDH1A1L3MBTL1 | |
| SCHEMBL4343354 | 0.76 | TSHR (0.71) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL6667676 | 0.75 | TSHR (0.79) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL27380 | 0.74 | TSHR (1.00) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL5311581 | 0.74 | TSHR (1.00) | TSHRCA1CA2CA7CA9 | |
| Benzene SCHEMBL27997624 | 0.74 | TSHR (1.00) | TSHRCA1CA2CA7CA9 | |
| Fluorobenzene SCHEMBL28333284 | 0.73 | TSHR (0.75) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374844-B | Pyrrolopyridazinone compound | UBE INDUSTRIES | 2012-10-24 | — | — | CN | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |