Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634302 | 0.79 | POLB (0.49) | POLBAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL129911 | 0.72 | SLC6A3 (0.46) | SLC6A3MEN1KMT2AADORA2A | |
| SCHEMBL27735625 | 0.70 | SMN1; SMN2 (0.35) | POLBAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL128514 | 0.67 | GABRA5 (0.39) | MEN1KMT2AGABRA5GABRB2HSD17B10 | |
| SCHEMBL6179952 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL28177526 | 0.66 | ALDH1A1 (0.38) | MEN1KMT2AGABRA5GABRB2HSD17B10 | |
| SCHEMBL27756233 | 0.66 | AKR1C3 (0.33) | POLBAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL4476254 | 0.66 | POLB (0.40) | POLBAKR1C3AKR1C2SLC6A3AKR1C1 | |
| SCHEMBL1548495 | 0.65 | DAO (0.39) | PDE5APOLBAKR1C3AKR1C2SLC6A3 | |
| SCHEMBL130878 | 0.65 | GABRA5 (0.34) | KMT2AGABRA5GABRB2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |